Clinical Trials

Cancer Type

State

Phase

Treatment

Inhibitor

A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors (LIBRETTO-121)

NCT 03899792 Brief Summary This is an open-label, multi-center Phase 1/2 study…

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A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT 06560645 Brief Summary This is a Phase 1 study to determine…

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A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001) (LIBRETTO-001)

NCT 03157128 Brief Summary This is an open-label, first-in-human study designed to…

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A Study of SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors

NCT 06063681 Brief Summary This is an open-label, dose-escalation, multi-center phase 1…

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A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ATG 037 Monotherapy and Combination Therapy With Pembrolizumab in Patients With Advanced Solid Tumors

NCT 05205109 Brief Summary This is a study of ATG-037 Monotherapy and…

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A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator’s Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer (rechARge)

NCT 06764485 Brief Summary The purpose of this study is to compare…

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A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

NCT 04913285 Brief Summary The purpose of this study is to evaluate…

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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

NCT 05487235 Brief Summary The purpose of this study is to evaluate…

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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

NCT 04449874 Brief Summary This is a Phase I dose-escalation and dose-expansion…

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A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of RO7589831 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumor

NCT 06004245 Brief Summary This is a first-in-human, Phase I, open-label, multicenter,…

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Knowledge Base

Cancer Types Cancer Services Health Professionals Clinical Trials

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