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Clinical Trials

Cancer Type

State

Phase

Treatment

Inhibitor

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

NCT 06926868 Brief Summary The purpose of this study is to assess…

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A Study of NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

NCT 05384626 Brief Summary Phase 1/2, dose escalation and expansion study designed…

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A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT 06560645 Brief Summary This is a Phase 1 study to determine…

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A Study of SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors

NCT 06063681 Brief Summary This is an open-label, dose-escalation, multi-center phase 1…

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A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ATG 037 Monotherapy and Combination Therapy With Pembrolizumab in Patients With Advanced Solid Tumors

NCT 05205109 Brief Summary This is a study of ATG-037 Monotherapy and…

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A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

NCT 06065748 Brief Summary This is a Phase III, randomized, open-label multicenter…

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A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

NCT 06179160 Brief Summary This study is conducted to determine the safety…

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A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

NCT 04913285 Brief Summary The purpose of this study is to evaluate…

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A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

NCT 07100106 Brief Summary The purpose of this study is to assess…

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A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

NCT 05894239 Brief Summary This study will evaluate the efficacy and safety…

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Knowledgebase

Cancer Types Cancer Services Health Professionals Clinical Trials

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