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MRI Guided Stereotactic Focal Ablation of Prostate Cancer investigating feasibility, Toxicity and Patient Reported Outcomes.

ACTRN 12623000902695

Brief Summary

This study is investigating the feasibility, safety and effectiveness of delivering targeted radiation therapy using a device with in-built magnetic resonance (MR) imaging to identify and deliver the radiation doses specifically to the prostate tumour.

Intervention/Treatment

  • Stereotactic Focal Ablation.

Inclusion Criteria

  1. Age 40yrs or older.
  2. WHO performance status 0-2.
  3. Life expectancy at least 10 years.
  4. Biopsy proven adenocarcinoma of the prostate.
  5. Low or favourable intermediate risk prostate cancer.
  6. PSA less than 20 ng/mL.
  7. Gleason score 7.
  8. Clinical T stage cT1c – cT2c.
  9. Solitary Tumours not more than 20mm in diameter on MRI; Tumour margins visible on MRI.
  10. Prostate Volume less than 100cc on TRUS.
  11. Willing and able to give written informed consent.

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