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A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma (inMMyCAR)

NCT 07075185

Brief Summary

The goal of this clinical trial is to evaluate the safety, tolerability, and recommended Phase 2 Dose (RP2D) of KLN-1010 in patients with relapsed or refractory multiple myeloma.

Intervention / Treatment 

  • Drug: KLN-1010

Inclusion Criteria:

  • Participants must have relapsed and refractory multiple myeloma (RRMM) with measurable disease.
  • Participants must have received at least 3 prior lines of therapy including a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and CD38-directed monoclonal antibody.
  • Participants must have an Eastern Cooperative Group (ECOG) performance status of 0-1.
  • Participants must have acceptable laboratory values as defined by the protocol.

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