Brief Summary
The MRI Linac is one of the newest and most technologically advancedat a late stage, far along radiotherapy machines used to treat cancera disease where abnormal cells split without control and spread to other nearby body tissue and/or organs. Magnetic resonance imagingtests that create detailed images of areas inside the body (MRI) is one of the best imaging tools available to guide radiotherapy. Linear accelerators (Linacs) are treatment machines used to deliver radiotherapy to treat cancers. By combining the MRI and Linac into an MRI-Linac, it allows the use of better images than standard X-rays to guide radiotherapy.
The purpose of this study is to determine if it is feasible to use the bespoke MRI-Linac at Liverpool Hospital to treat patients. The data collected will be used in developing and improving the MRI-Linac for future cancer patients.
Intervention/Treatment
- Device: MRI-Linac.
Inclusion Criteria
- 18 years or older.
- Have the ability to give informed consenta process in which a patient receives detailed information about a procedure or treatment, including its potential risks, benefits, and alternatives. The patient then has the opportunity to understand the information and voluntarily agree to the procedure or treatment. with the clear understanding that this is a prototype cancer radiation therapya treatment that uses controlled doses of radiation to damage or kill cancer cells system and not a commercially available and supported system.
- A diagnosisthe process of identifying a disease based on signs and symptoms, patient history and medical test results of cancer with a palliative indication for radiotherapy and referral to the Liverpool or Macarthur Cancer Therapy Centres.
- A treatment site and prognosisto predict how a disease/condition may progress and what the outcome might be that, in the opinion of the treating physician, is clinically appropriate for this MRI-Linac feasibility trial using conformal radiotherapy in consultation with medical physicists and radiation therapists. The treatment fields used for planning must be able to be accommodated for the particular patient on the MRI-Linac. Examples may include (but are not restricted to) patients presenting with:
- Cervical-spine metastasiswhen the cancer has spread to other parts of the body, also known as mets.
- Whole brain.
- Recurrent brain metastasis.
- Bone metastasis.
- Soft tissuetissue/the material that joins, holds up or surrounds inside body parts such as fat, muscle, ligaments and lining around joints metastasis.
- ECOG status 0-2.